In this study, we determined the complete coding sequence of a putative new member of the family Flaviviridae, named "Cyclopterus lumpus virus" (CLuV), which is associated with a serious disease in lumpfish (Cyclopterus lumpus). The virus was present in all tissues tested, but pathology was primarily observed in the liver and kidneys. CLuV shows low but distinct similarity to the unassigned Tamana bat virus (TABV). Unlike other known members of the family Flaviviridae, translation of the entire CLuV polyprotein is dependent on a - 1 ribosomal frameshift in the NS2A region.
Notes
Cites: Dis Aquat Organ. 2000 Feb 24;40(1):9-18 PMID 10785858
Cites: Pest Manag Sci. 2014 Aug;70(8):1274-82 PMID 24293262
Cites: J Fish Dis. 2013 Mar;36(3):171-94 PMID 23311858