Iron deficiency is often observed in obese individuals. The iron regulatory hormone hepcidin is regulated by iron and cytokines interleukin (IL) 6 and IL1ß. We examine the relationship between obesity, circulating levels of hepcidin, and IL6 and IL1ß, and other risk factors in patients with nonalcoholic fatty liver disease (NAFLD) with iron deficiency.
We collected data on 675 adult subjects (>18 years old) enrolled in the Nonalcoholic Steatohepatitis Clinical Research Network. Subjects with transferrin saturation