The association between eating disorders and migraine remains unclear.
We identified women with lifetime diagnoses of anorexia nervosa (AN) (N?=?55) and bulimia nervosa (BN) (N?=?60) and their co-twins from the FinnTwin16 cohort born in 1975-1979 (N?=?2,825 women). Eating disorder and major depressive disorder (MDD) diagnoses were obtained from clinical interviews and data on migraine by self-report questionnaire. The women with eating disorders were compared with their unaffected co-twins and with unrelated women from the same birth cohorts.
The prevalence of migraine was 12% in the general female population, but 22% for both AN and BN (odds ratio 2.0, p?=?.04). The prevalence of MDD was high in women with an eating disorder (42%). MDD was strongly associated with migraine (odds ratio 3.0, p?