Occupational exposure to irritants is associated with chronic bronchitis. The aim of this study was to elucidate whether repeated peak exposures with respiratory symptoms, gassings, to sulphur dioxide (SO2) and other irritant gases could increase the risk of chronic bronchitis.
The study population comprised 3,060 Swedish pulp mill workers (84% males) from a cohort study, who completed a comprehensive questionnaire with items on chronic bronchitis symptoms, smoking habit, occupational history, and specific exposures, including gassings. 2,037 have worked in sulphite mills. Incidence rates and hazard ratios (HRs) for the observation period, 1970-2000, in relation to exposure and the frequency of repeated gassings to SO2 and other irritant gases were calculated.
The incidence rate for chronic bronchitis among workers with repeated gassings was 3.5/1,000 person-years compared with 1.5/1,000 person-years among unexposed workers (HR 2.1, 95% confidence interval (CI) 1.4-3.1). The risk was even higher in the subgroup with frequent gassings (HR 3.2, 95% CI 2.0-5.2), particularly among never-smokers (HR 8.7, 95% CI 3.5-22).
Repeated gassings to irritant gases increased the incidence of chronic bronchitis in our study population during and after work in pulp mills, supporting the hypothesis that occupational exposures to irritants negatively affect the airways. These results underscore the importance of preventive actions in this work environment.
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Cites: Ann Occup Hyg. 2008 Mar;52(2):107-1518216372
Cites: Int Arch Occup Environ Health. 2010 Feb;83(2):123-3219636585
Cites: Respir Med. 2010 Mar;104(3):323-420036524
Cites: BMC Public Health. 2011;11:68921896193
Cites: Int J Tuberc Lung Dis. 2012 Apr;16(4):553-722325166
Cites: Eur Respir J. 1999 Oct;14(4):828-3110573229
Cites: Am J Ind Med. 2000 Oct;38(4):385-810982978
Cites: Scand J Work Environ Health. 2002 Oct;28(5):328-3212432986
Cites: J Occup Environ Med. 1998 Nov;40(11):986-939830606
Cites: Scand J Work Environ Health. 1998 Feb;24(1):12-79562396
Cites: Lancet. 1997 May 3;349(9061):1316-89142078
Cites: Chest. 2005 Oct;128(4):3028-3716236983
Cites: Am J Respir Crit Care Med. 2005 Nov 1;172(9):1139-4516040784