The results obtained concern the dependence of acute brain blood circulation pathology (ABBCP) frequency on several meteorological factors: wind speed, barometrical pressure, interdaily barometrical pressure changes, relative air humidity, air temperature, interdaily air temperature changes, oxygen content in air and interdaily oxygen content variability in the air. The mean daily number of patients was taken into account. 4023 ABBCP observations were analyzed. Wind, relative air humidity and interdaily changes of oxygen content in air were determined to influence greatly the ABBCP frequency under conditions of Middle Russia Hills region. Meteorological factors enumerated are supposed to be used in further multifactorial statistical analyses for comprehensive estimation of weather elements as well as for scientifically based prognoses of the ABBCP number and carrying out the preventive measures.