To examine the combined influence of workplace demands and changes in blood pressure induced by stress on the progression of carotid atherosclerosis.
Population based follow up study of unestablished as well as traditional risk factors for carotid atherosclerosis, ischaemic heart disease, and other outcomes.
Eastern Finland.
591 men aged 42-60 who were fully employed at baseline and had complete data on the measures of carotid atherosclerosis, job demands, blood pressure reactivity, and covariates.
Change in ultrasonographically assessed intima-media thickness of the right and left common carotid arteries from baseline to 4 year follow up.
Significant interactions between workplace demands and stress induced reactivity were observed for all measures of progression (P