The aim of the present cross-sectional study was to investigate the relationship between urinary albumin excretion and insulin sensitivity, intact insulin and insulin propeptides in 104 clinically healthy 58-year-old men recruited from the general population. Insulin sensitivity (hyperinsulinemic euglycemic clamp) adjusted for lean body mass, fasting plasma insulin, proinsulin, split-proinsulin, C-peptide, and urinary albumin excretion and were determined. Urinary albumin excretion was significantly associated with body mass index (BMI), systolic and diastolic blood pressure, plasma insulin, and C-peptide (P