The article reviews present-day data on pathogenesis of chronic venous diseases, as well as formulates the strategic missions of treatment, with an emphasis placed on the criteria ol evidence-based medicine, followed by critically analysing the standards of pharmacotherapy of chronic venous diseases, reflected in the European, American and Russian clinical guidelines. A conclusion is drawn on the necessity and advisability, from the point of view ol evidence-based medicine, of using phlebotropic drugs in patients suffering from various forms of chronic venous diseases.