Association between obesity history and hand grip strength in older adults--exploring the roles of inflammation and insulin resistance as mediating factors.
Department of Health, Functional Capacity and Welfare, National Institute for Health and Welfare, Peltolantie 3, FI-20720 Turku, Finland. sari.stenholm@thl.fi
Source
J Gerontol A Biol Sci Med Sci. 2011 Mar;66(3):341-8
To examine the association between obesity history and hand grip strength, and whether the association is partly explained by subclinical inflammation and insulin resistance.
Data are from 2,021 men and women aged 55 years and older participating in the representative population-based Health 2000 Survey in Finland. Body mass and body height, maximal hand grip strength, C-reactive protein, and insulin resistance based on homeostasis model assessment (HOMA-IR) were measured in a health examination. Recalled weight at 20, 30, 40, and 50 years of age were recorded to obtain a hierarchical classification of obesity history. Obesity was defined as body mass index = 30 kg/m².
Earlier onset of obesity was associated with lower hand grip strength (p