Patients suffering from heart diseases often face lifelong oral anticoagulant therapy. Traditionally, the patient's general practitioner takes care of the treatment. An alternative management scheme is a self-monitoring setup where the patient monitors and manages the oral treatment himself. Despite international evidence of reduced thrombosis risk and death rate among patients enrolled in self-monitoring, a majority of eligible patients deselect this opportunity. Little is about the causes if this. This study is a pilot assessment of why patients, located in the North Denmark Region, choose not to participate. The study is based on qualitative interviews with two nurses working in a medical practice and two patients participating in conventional anticoagulant therapy. The results of this study seem to suggest that at least some patients feel a lack of information to base their decision regarding self-monitoring or conventional management on and that the knowledge among the health personnel at the medical clinics should be increased.