Visceral adipose tissue (VAT) is associated with abnormal cardiovascular and metabolic profiles. Total VAT volume of the abdominal compartment by magnetic resonance imaging (MRI) is the gold-standard measurement for VAT but is costly and time consuming. Prior studies suggest VAT area on a single slice MR image may serve as a surrogate for total VAT volume but it is unknown if this relationship is maintained in overweight and obese men and women. Untreated sleep apnea subjects enrolled into the Icelandic Sleep Apnea Cohort (ISAC) underwent abdominal MRI. VAT area and subcutaneous adipose tissue (SAT) area at the L2-L3 and L4-L5 interspaces and total VAT and SAT volumes were determined by manual examination using image analysis software; 539 men and 129 women with mean ages of 54.1 and 58.8 years and mean BMI of 32.2 kg/m(2) and 33.7 kg/m(2), respectively, were studied. Mean total VAT volume was 40% smaller and mean total SAT was 25% larger among females compared with males. The correlation with VAT volume was significantly larger for L2-L3 VAT area (r = 0.96) compared to L4-L5 VAT area (r = 0.83). The difference in correlation coefficients was statistically significant (nonparametric bootstrap P
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Cites: Am J Clin Nutr. 1991 Oct;54(4):623-71897468
Cites: Am J Clin Nutr. 2004 Aug;80(2):271-815277145
Cites: Am J Clin Nutr. 1993 Apr;57(4):470-58460599
Cites: Ann Epidemiol. 1990 Oct;1(1):33-481669488
Cites: Am J Clin Nutr. 1994 Jun;59(6):1277-858198051
Cites: J Lipid Res. 1994 Aug;35(8):1490-67989873
Cites: Can J Physiol Pharmacol. 1996 Jun;74(6):778-858909791
Cites: Am J Clin Nutr. 1997 Feb;65(2):403-89022523
Cites: Int J Obes Relat Metab Disord. 1997 Dec;21(12):1161-69426384