Department of Pediatrics, Division of Pediatric Nephrology, Children's Hospital, London Health Science Centre, University of Western Ontario, London ON, Canada.
To assess the influence of height age and short stature on BMI z-scores in children with chronic kidney disease (CKD) in view of the pandemic increase of childhood obesity.
Pediatric nephrology patients older than 2 years of age from 2 tertiary centers in Ontario and age- and gender matched controls from a local reference population.
We estimated height, weight and body mass index (BMI) z-scores of 705 nephrology patients (319 female) and 4,196 controls aged 2.01 - 19.92 years with chronological and height-adjusted age (corresponding age for a given height plotted on the 50th percentile). The National Health and Nutrition Examination Survey (NHANES III) was used for the z-score Estimation.
Chronological age-based patient weight z-scores were significantly heavier than in the NHANES data (median weight z-score +0.29, BMI z-score +0.51; significantly non-zero), not significantly different from height-adjusted age-based BMI z-score (+0.51). The children with kidney problems were shorter (-0.10 SD) than controls.
The proportion of overweight nephrology patients was similar to matched controls and BMI z-score diminished with worsening GFR.