The article contains data about the peculiarities of indicators of the quality of life in elderly migrants of the Far North with arterial hypertension in the period of readaptation to new climatic conditions. Migrants of the Far North and residents of Krasnoyarsk revealed a moderate decline in the quality of life. Among all the factors reducing the quality of life of the subjects of study the most important is the need to be treated and to take drugs for chronic diseases. At the same time, the migrants of the Far North demonstrated a great reduction of the quality of life due to reduced activity in everyday life, dietary restrictions. The inhabitants of Krasnoyarsk showed the same due to reduction of income at retirement, reduced physical activity. At increase the terms of residence on arrival in the southern regions of Central Siberia the proportion of studied people with normal quality of life proved to be reduced and number of persons with a significantly reduced quality of life increases.