Columbia University, New York, New York, U.S.A. Karolinska Institutet, Stockholm, Sweden UCL Institute of Neurology, Queen Square, London, United Kingdom SEIN - Epilepsy Institute in the Netherlands Foundation, Heemstede, The Netherlands Department of Neurological Rehabilitation, Stora Sköndal Hospital, Stockholm, Sweden University of Minnesota, Minneapolis, Minnesota, U.S.A. Mario Negri Institute, Milan, Italy University of Glasgow, Glasgow, United Kingdom.
Purpose: To pool data from four published case-control studies of sudden unexpected death in epilepsy (SUDEP) with live controls, to increase the power to determine risk factors. Methods: Case-control studies from the United States, Sweden, Scotland, and England were combined. SUDEP was defined as (1) a history of epilepsy (>1 epileptic seizure during a period of