Encephalitis after influenza in Sweden 1987-1998: a rare complication of a common infection.

https://arctichealth.org/en/permalink/ahliterature89622
Source
Eur Neurol. 2009;61(5):289-94
Publication Type
Article
Date
2009
Author
Hjalmarsson Anders
Blomqvist Paul
Brytting Maria
Linde Annika
Sköldenberg Birgit
Author Affiliation
Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden. anders.hjalmarsson@ki.se
Source
Eur Neurol. 2009;61(5):289-94
Date
2009
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Aged, 80 and over
Child
Encephalitis, Viral - epidemiology - etiology - mortality
Female
Humans
Incidence
Influenza, Human - complications - epidemiology - mortality
Male
Middle Aged
Registries
Sweden - epidemiology
Young Adult
Abstract
The aim of this study was to investigate the incidence of influenza-related encephalitis in Sweden during 11.5 years. Studies from Japan report an increased incidence of influenza-related encephalitis/encephalopathy. Few other studies are available. We conducted a retrospective register-based study on the Swedish National Inpatient Register, which covers all Swedish hospitals. In 1987-1998, a total number of 14,250 hospitalized individuals had an influenza diagnosis (population incidence: 137 per million person-years). In-hospital mortality was 4.1%. Using three different approaches, only 21 cases of influenza-related encephalitis were found, corresponding to a rate of 1.5 per 1,000 hospitalized persons with an influenza diagnosis (population incidence 0.21 per million person-years). We conclude that encephalitis following influenza occurs rarely, or is an infrequently recognized, diagnosed or reported complication. The cases we studied in detail have all recovered without sequels.
PubMed ID
19295216 View in PubMed
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