[Preventive hepatitis B vaccination of hospital staff]

https://arctichealth.org/en/permalink/ahliterature56856
Source
Ugeskr Laeger. 1992 Aug 31;154(36):2421-3
Publication Type
Article
Date
Aug-31-1992
Author
L S Jepsen
A C Thomsen
Author Affiliation
Medicinsk afdeling B, Bispebjerg Hospital, København.
Source
Ugeskr Laeger. 1992 Aug 31;154(36):2421-3
Date
Aug-31-1992
Language
Danish
Publication Type
Article
Keywords
Denmark
English Abstract
Hepatitis B - immunology - prevention & control
Hepatitis B vaccines - administration & dosage
Humans
Immunization
Personnel, Hospital
Vaccines, Synthetic - administration & dosage
Abstract
In March 1990, a vaccination campaign against hepatitis B was organized in a municipal hospital in Copenhagen (Bispebjerg Hospital). The hospital staff (830 subjects) at risk of infection with hepatitis B were offered vaccination with Engerix B. The vaccination was given as Engerix B (recombinant DNA vaccine) in muscle deltoid after 0, 1 and 6 months. Antibody level was measured after one month. A total of 362 (44%) received vaccination against hepatitis B and 86% of these completed the vaccination schedule and received at least three vaccinations. 95% of the vaccinated subjects were protected after three vaccinations (HBsAg more than 10 IU/l). Conclusion: The recombinant DNA vaccine does not differ from the plasma-derived vaccine concerning immunogenicity and adverse reactions. There was a low compliance with the vaccination campaign, especially among doctors (35%) and laboratory technicians (35%), despite central organization.
PubMed ID
1413161 View in PubMed
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