Extent of heterogeneity in mitochondrial DNA of European populations.

https://arctichealth.org/en/permalink/ahliterature208627
Source
J Forensic Sci. 1997 May;42(3):437-46
Publication Type
Article
Date
May-1997
Author
T. Melton
M. Wilson
M. Batzer
M. Stoneking
Author Affiliation
Pennsylvania State University, University Park, USA.
Source
J Forensic Sci. 1997 May;42(3):437-46
Date
May-1997
Language
English
Publication Type
Article
Keywords
Analysis of Variance
Base Sequence
DNA, Mitochondrial - analysis - classification
Europe
Genetic Heterogeneity
Humans
Oligonucleotide Probes - genetics
Polymorphism, Genetic
Abstract
Variation in the mitochondrial DNA (mtDNA) control region as detected by sequence-specific oligonucleotide (SSO) probes is described for 595 individuals from six European or European-derived populations. Estimates of diversity for mtDNA types exceed 0.91 in all populations, while 50% of the 158 types which were observed occur only once. Of 68 shared types, most occur rarely ( 0.001), and these groups are virtually indistinguishable with respect to mtDNA SSO types. These results demonstrate the utility of mtDNA typing for forensic investigations.
PubMed ID
9144933 View in PubMed
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