Liver transplantation in patients over 60 years of age.

https://arctichealth.org/en/permalink/ahliterature196366
Source
Transpl Int. 2000;13 Suppl 1:S165-70
Publication Type
Article
Date
2000
Author
K. Bjøro
K. Höckerstedt
B G Ericzon
S. Friman
A. Hjortrup
S. Keiding
E. Schrumpf
F. Duraj
M. Olausson
H. Mäkisalo
A. Bergan
P. Kirkegaard
Author Affiliation
Department of Medicine A, Rikshospitalet, Oslo, Norway.
Source
Transpl Int. 2000;13 Suppl 1:S165-70
Date
2000
Language
English
Publication Type
Article
Keywords
Age Distribution
Age Factors
Aged
Creatinine - blood
Humans
Liver Transplantation - mortality - physiology - statistics & numerical data
Middle Aged
Prothrombin Time
Retrospective Studies
Scandinavia
Serum Albumin - analysis
Survival Rate
Time Factors
Transplantation, Homologous
Treatment Outcome
Abstract
Liver transplantation was previously only offered to patients under 60 years of age. We have analyzed the outcome after acceptance on the waiting list and after liver transplantation of patients over 60 years old. A total of 150 patients over 60 years old were listed for a first liver transplantation during 1990-1998. The annual number increased throughout the period. Primary biliary cirrhosis, primary sclerosing cholangitis, and acute hepatic failure were the most frequent diagnoses. A total of 119 patients received a first liver allograft. The patient 1-year survival was 75% and 3-year survival 62%, which was not significantly lower (P = 0.21) than that of the younger patients. When correcting for year of transplantation, the survival was, however, moderately but significantly lower than among the younger patients. Survival among those > 65 years (n = 38) did not differ from that of patients 60-65 years of age (n = 81). We conclude that an increasing number of patients over 60 years old can be listed for liver transplantation and receive a liver allograft with highly satisfying results.
PubMed ID
11111989 View in PubMed
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