The prevalence of celiac disease in blood donors in Iceland.

https://arctichealth.org/en/permalink/ahliterature156325
Source
Dig Dis Sci. 2009 Feb;54(2):348-50
Publication Type
Article
Date
Feb-2009
Author
Gudmundur F Johannsson
Gudjon Kristjansson
Nick Cariglia
Vigfus Thorsteinsson
Author Affiliation
Department of Medicine, FSA University Hospital, 600, Akureyri, Iceland.
Source
Dig Dis Sci. 2009 Feb;54(2):348-50
Date
Feb-2009
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Blood Donors - statistics & numerical data
Celiac Disease - epidemiology
Female
Humans
Iceland - epidemiology
Male
Middle Aged
Prevalence
Prospective Studies
Young Adult
Abstract
Prospective epidemiological studies based on serological methods have shown that celiac disease is more common than previously thought. The aim of this study was to evaluate the prevalence of celiac disease among apparently healthy blood donors in Iceland.
Plasma samples were obtained from 813 apparently healthy blood donors at the FSA Hospital Blood Bank in Akureyri, Iceland, between December 2004 and January 2007 and screened for human tissue transglutaminase IgA antibodies. Positive samples were retested and, if the test was again positive, the subject was referred to a gastroenterologist for clinical examination and a duodenoscopy with mucosal biopsies.
Six subjects tested positive for tissue transglutaminase. The prevalence of biopsy-confirmed celiac disease, according to modified Marsh classification, among apparently healthy blood donors in Iceland was found to be 1:136 (0.74%, 95% confidence interval 1/667-1/75, 0.15-1.33%).
Prevalence of celiac disease in Iceland is similar to what has been reported in many other countries.
PubMed ID
18600451 View in PubMed
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