Renal tumors and the risk of malignancy based on size.

https://arctichealth.org/en/permalink/ahliterature146750
Source
Can J Urol. 2009 Dec;16(6):4921-3
Publication Type
Article
Date
Dec-2009
Author
Behrooz Azizi
Thomas Whelan
Michael Morse
Author Affiliation
St George's University School of Medicine, Grenada.
Source
Can J Urol. 2009 Dec;16(6):4921-3
Date
Dec-2009
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Carcinoma, Renal Cell - diagnosis - epidemiology - surgery
Diagnosis, Differential
Female
Follow-Up Studies
Humans
Incidence
Kidney Neoplasms - diagnosis - epidemiology - surgery
Male
Middle Aged
Neoplasm Staging - methods
Nephrectomy
Nova Scotia - epidemiology
Retrospective Studies
Abstract
To determine the incidence of malignancy in resected renal tumors in a subpopulation of Canadian patients and the significance of tumor size, patient's demographics, and whether the tumor was an incidental finding.
Medical records of 168 consecutive nephrectomies performed between March 2003 and June 2008 at our institution were reviewed retrospectively.
Average age of the patients was 61 years old (SD 11, range 28-89) and male to female ratio was 1.3:1. Total of 180 masses were resected in 168 nephrectomies (128 radical, 40 partial) during the study period. Of the 180 masses, 20 (11%) were benign and 160 (89%) were malignant lesions. Fifty-five percent of the resected renal masses were incidentally found on preoperative imaging. Based on the pathology reports, the average size of the masses was 5.5 cm (SD 4.0, range 0.3-25.0). The larger masses were more likely to be malignant than the smaller masses (Pearson's chi-square test, p = 0.040).
The present study assists us to adequately assess the risk of malignancy of a renal mass in a Canadian population based on size which allows us to properly advise the patients and suggest best possible treatment options. We recommend more aggressive therapies for masses larger than 4 cm and parenchymal sparing procedures for masses smaller than 4 cm as large proportion of these are benign.
PubMed ID
20003669 View in PubMed
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