Relation between renal function, presentation, use of therapies and in-hospital complications in acute coronary syndrome: data from the SWEDEHEART register.
Department of Medicine, Section of Cardiology, Huddinge, Karolinska Institute, Karolinska University Hospital, Stockholm. karolina.szummer@karolinska.se
OBJECTIVE: To examine clinical characteristics, presenting symptoms, use of therapy and in-hospital complications in relation to renal function in patients with myocardial infarction (MI). DESIGN: Observational study. SETTING: Nationwide coronary care unit registry between 2003-2006 in Sweden. SUBJECTS: Consecutive MI patients with available creatinine (n = 57,477). RESULTS: Glomerular filtration rate was estimated with the Modification of Diet in Renal Disease Study formula. With declining renal function patients were older, had more co-morbidities and more often used cardio-protective medication on admission. Compared to patients with normal renal function, fewer with renal failure presented with chest pain (90% vs. 67%, P