[Frequency of the Pro 12Ala polymorphism of PPARgamma2 gene in Ukrainian population and its possible role in development of metabolic syndrome] • Arctic Health

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[Frequency of the Pro 12Ala polymorphism of PPARgamma2 gene in Ukrainian population and its possible role in development of metabolic syndrome]

https://arctichealth.org/en/permalink/ahliterature93638

Source: Tsitol Genet. 2007 Sep-Oct;41(5):43-7

Publication Type: Article

Author: Kaidashev I P; Rasin A M; Shlykova O A; Gorbas' I M; Smirnova I P; Petrushov A V; Rasin M S

Source: Tsitol Genet. 2007 Sep-Oct;41(5):43-7

Language: Russian

Publication Type: Article

Keywords: Adult; Aged; Alanine - genetics; Blood pressure; Body mass index; DNA - genetics; European Continental Ancestry Group; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Metabolic Syndrome X - epidemiology - genetics; Middle Aged; PPAR gamma - genetics; Polymorphism, Genetic; Proline - genetics; Ukraine - epidemiology

Abstract: Frequency of the Pro 12Ala gene polymorphism PPARg2 has been studied in 39 healthy men and 42 men with metabolic syndrome (MS) of the age of 40-65 years in Ukrainian population. The frequencies were 27.9% for 12Ala allele, 32.6% for Pro12Ala, and 4.4% for Ala1Ala that is close to the results of estimation of Czech population. The frequency of 12Ala allele was significantly less--18.4% (p

PubMed ID: 18268966 View in PubMed