The course of infiltrative tuberculosis making up 53.2% in the pattern of clinical forms was investigated in 64 adolescents. Infiltrative tuberculosis morbidity among the girls is 3 times higher. The main detection method is represented by a planned roentgenofluorographic examination, since in the region in question infiltrative tuberculosis tends to have limited symptoms in 56.2% of the adolescents, including 30.5% of them even with disseminated process. In 60.9% of the cases, infiltrative tuberculosis is observed to have a decomposition phase which is 4.5 times more frequently traced in patients living in contact with a bacillary ++carrier . In 8% of the patients, infiltrative tuberculosis was complicated by hemoptysis. Infiltrative tuberculosis in 32.8% of the adolescents manifests itself in a pulmonary form of primary tuberculosis. Due to a complex treatment hemodynamic indices are normalized by the end of the first month in addition to the removal of the intoxication signs by the third month. Cavity closure was achieved in 71.8% of the patients. Despite the given therapy, transformation into the destructive forms of tuberculosis took place.