Drugline is a problem-oriented drug information data base. The information available is based on queries submitted by health care professionals, mainly physicians, to the Drug Information Center (DIC), Huddinge University Hospital, Sweden. Clinical pharmacologists and pharmacists evaluate relevant information from medical publications, and queries are answered individually with a referenced review of pertinent literature. Most queries deal with adverse drug reactions or the safety of drug treatment during pregnancy or breast feeding. A joint project, undertaken by Huddinge's DIC and the National Corporation of Swedish Pharmacies (Apoteksbolaget), aims to promote Drugline and the institution of DICs at university hospitals throughout the country.