The role of meteotropic factors (low atmospheric pressure and cold climate) in the development of functional disorders of respiratory system was studied for miners of the North-East region of the USSR. Regularities in forming external respiration dysfunctions during adaptation of migrating population and development of dust pathology are demonstrated. It was found that general adaptation syndrome in miners exposed to chronic hypobaric hypoxia and hypothermia is characterized by development of hyperventilation syndrome, leading to increase in dust load and moderate mobilization of respiratory tissue. Early failure of compensatory processes and forming of marked hyperventilation syndromes, an increase in pulmonary elastic draught and mobilization of respiratory tissue are observed in dust pathology in the analyzed conditions.