Institute of Clinical and Experimental Lymphology, Siberian Division, Russian Academy of Medical Sciences, ul. Timakova, 2, Novosibirsk, 630117 Russia.
The enterosorbent noolit (representing a mineral matrix base with immobilized lithium and silicon compounds) significantly affects the psychoemotional state of mice with depression model induced by prolonged social emotional stress. Noolit administration produces a pronounced anxiolytic and antidepressant effect and reduced the level of behavioral deficiency in the test animals.