A mailed questionnaire assessed personality traits of a cohort of 194 subjects followed from 1988 to 1998 measured by the Karolinska Scales of Personality and Sense of Coherence Scale, medical symptoms, and 3 VAS scales on Perceived Psychosocial Work Satisfaction. Subjects initially worked in 19 Swedish buildings with indoor environmental problems. There was a relatively high correlation between SOC scores and KSP scale scores (R2=.54 in men and .55 in women), and there was a sex-KSP interaction on the association between the two sets of scores. An increase of symptom score (SC difference) during the follow-up period was associated with higher psychic anxiety (p