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A prospective cohort analysis of gut microbial co-metabolism in Alaska Native and rural African people at high and low risk of colorectal cancer.
https://arctichealth.org/en/permalink/ahliterature307637
Source
Am J Clin Nutr. 2020 02 01; 111(2):406-419
Publication Type
Journal Article
Observational Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Date
02-01-2020
More detail
Author
Soeren Ocvirk
Annette S Wilson
Joram M Posma
Jia V Li
Kathryn R Koller
Gretchen M Day
Christie A Flanagan
Jill Evon Otto
Pam E Sacco
Frank D Sacco
Flora R Sapp
Amy S Wilson
Keith Newton
Faye Brouard
James P DeLany
Marissa Behnning
Corynn N Appolonia
Devavrata Soni
Faheem Bhatti
Barbara Methé
Adam Fitch
Alison Morris
H Rex Gaskins
James Kinross
Jeremy K Nicholson
Timothy K Thomas
Stephen J D O'Keefe
Author Affiliation
Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Source
Am J Clin Nutr. 2020 02 01; 111(2):406-419
Date
02-01-2020
Language
English
Publication Type
Journal Article
Observational Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Keywords
Adult
African Continental Ancestry Group
Alaskan Natives
Bacteria - classification - metabolism
Cohort Studies
Colorectal Neoplasms - epidemiology - genetics - microbiology
Cross-Sectional Studies
Diet
Female
Gastrointestinal Microbiome - physiology
Humans
Male
Middle Aged
Prospective Studies
RNA, Bacterial - genetics
RNA, Ribosomal, 16S - genetics
Rural Population
Abstract
Alaska Native (AN) people have the world's highest recorded incidence of sporadic colorectal cancer (CRC) (~91:100,000), whereas rural African (RA) people have the lowest risk (
PubMed ID
31851298
View in PubMed
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