This paper first explains why the specific words were selected for the title, as there have been great changes in the way science is conducted in recent years. A short history is provided of key events over the past fifty years that have contributed significantly to the national and international efforts in northern investigations. An overview of the Inuit efforts to partner in health science research is presented, including some past examples of collaboration. The aspects to consider in promoting the current practice of community-based participatory research among partners are provided. A comparison is made between the evolution of co-management approaches for the joint administration of living resources, and the shifts that are occurring in how health research is being conducted. The recommendation is made such that the governmental institutions that work with health programs of the eight-nation Arctic Council, should orchestrate a coordination committee that brings together the residents, the providers, and the investigators, to address the health disparities and regional capacities to conduct coordinated circumpolar investigations. This forum is also proposed to forge links with other federal agency programs that are providing healthrelated research in the polar region.