The Icelandic Heart Association, Kopavogur, Iceland; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden. Electronic address: larsef@me.com.
Quantitative analyses of brain structures from Magnetic Resonance (MR) image data are often performed using automatic segmentation algorithms. Many of these algorithms rely on templates and atlases in a common coordinate space. Most freely available brain atlases are generated from relatively young individuals and not always derived from well-defined cohort studies. In this paper, we introduce a publicly available multi-spectral template with corresponding tissue probability atlases and regional atlases, optimised to use in studies of ageing cohorts (mean age 75 ± 5 years). Furthermore, we provide validation data from a regional segmentation pipeline to assure the integrity of the dataset.
Notes
Cites: Neuroimage. 2010 Feb 1;49(3):2352-65 PMID 19857578