The article considers issues of effectiveness of management of human health in conditions of innovative development of society. The study was carried out to investigate functional condition of health of students in dynamics as compared with health indices of other population groups, to develop health promotion ideology and motivation for implementation of health culture and health preservation. The sampling consisted of 800 healthy volunteers out of various regions of Russia aged 17-60 years (males - 50%, females - 50%) having active social life-style and without chronic pathologies. The Martine-Kushelevskii test was applied for examination. The data was analyzed using technique of single-factor analysis of variance. It is established that number of individuals with health condition and estimated as "good" reliably decreased in the group of 17-20 years up to 13%, in the group of 21-30 years up to 6.7%, in the group of 31-49 years up to 3.3%, in the group of 41-50 years up to 3.3% during 6 years of observation. The number of volunteers with estimate "satisfactory" has a trend to decreasing in all groups. In the group 17-20 years' number of examinees with satisfactory values is significantly lower than in other age groups. The study data permits to conclude that it is necessary to introduce the passport of health reflecting both medical indices and individual algorithm of health. This algorithm will be a multifactorial indicator of stress resistance and capacity to adaptation.