Department of Environmental Medicine, University of Southern Denmark, J.B. Winsløws Vej 17A, 5000 Odense C, Denmark. Electronic address: atimmermann@health.sdu.dk.
The aim of this study was to determine whether maternal exposure to persistent perfluoroalkyl substances (PFASs) affect the capability to breastfeed. In two Faroese birth cohorts (N=1130), concentrations of five PFASs were measured in maternal serum during pregnancy or two weeks after term. Duration of breastfeeding was assessed by questionnaire and clinical interview. In adjusted linear regression models, a doubling of maternal serum PFASs was associated with a reduction in duration of both total and exclusive breastfeeding, most pronounced for perfluorooctane sulfonic acid (PFOS) where a doubling was associated with a reduction in total breastfeeding of 1.4 (95% CI: 0.6; 2.1) months and perfluorooctanoic acid (PFOA) where a doubling was associated with a reduction in exclusive breastfeeding of 0.5 (0.3; 0.7) months. The associations were evident among both primiparous and multiparous women, and thus cannot be explained by confounding from previous breastfeeding.
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Cites: Environ Sci Technol. 2012 Aug 21;46(16):9071-9 PMID 22770559
Cites: Am J Public Health. 2003 Dec;93(12):2000-10 PMID 14652321
Cites: Environ Sci Technol. 2006 Jun 1;40(11):3463-73 PMID 16786681