The aim of the present nationwide Danish cohort study was to examine the association between body mass index (BMI) and reoperation in patients who are sur-gically treated for perforated peptic ulcer (PPU).
This was a nationwide cohort study of all Danish patients who were surgically treated for benign gastric or duodenal PPU between 2011 and 2013.
reoperation within 30 days of the primary surgical procedure and 90-day survival. The association between BMI and reoperation are presented as crude and adjusted odds ratios (OR) with 95% confidence intervals (CIs).
A total of 726 patients were included. The median age was 69.5 years (range: 18.2-101.7 years), 51.4% were women (n = 373), 78.4% (n = 569) of the patients had at least one co-existing disease, and 47.5% (n = 345) were categorised as American Society of Anesthesiologists (ASA) class = 3. Re-operative surgery was done in 124 patients (17.1%). No statistically significant adjusted association between underweight, overweight or obesity and re-operation was found (adjusted OR (95% CI): 0.456 (0.181-1.148), 1.468 (0.857-2.517), and 1.314 (0.663-2.601), respectively). Patients undergoing reoperative surgery had a statistically significantly lower crude 90-day survival than patients without need of reperative surgery; 63.9% (83/124) versus 75.9% (457/602), p = 0.037.
In the present nationwide cohort study of PPU patients, no statistically significantly adjusted correlation between BMI and re-operation rates was found. Patients undergoing reoperative surgery had a decreased 90-day survival.