The incidence of the postoperative atrialfibrillation (POAF) after open heart surgery is up to 65%. Statin therapy has shown conflicting data in the prevention of the POAF.
Our aim was eo evaluate the role of statin therapy in the primary prevention of AF after CABG.
Group 1 (n = 82) included those patients who received no statin therapy and the Group 2 (n = 124) included those patients who did receive statin therapy for at least three days prior to the operation and for all days in the postoperative period. WBC count in different periods after surgery and rate of AF were evaluated. The risk of occurrence of postoperative AF was evaluated using the Cox-regression model and odds ratio.
A retrospective analysis of 206 medical records of the patients without pre-existing AF after CABG was performed. The rate of AF was 26% in Group 1 and 6.5 % in Group 2 (p = 0.0001). On Day 4 after surgery, WBC count was 11 (9;13) in the first group and 9 (7.6;10.2) x 10(9) e/L in the second group (p = 0.000001). "Statin use" and "number of grafts" and were found to be statistically meaningful: p = 0.002 and p = 0.0125 respectively (?2 = 28.3; p