To examine the association between self-reported memory failures and incident dementia in individuals aged 60 and older.
Longitudinal, community based.
Betula Prospective Cohort Study, a population-based study in Umeå, Sweden.
Individuals with a mean age of 71.5 ± 8.8 (range 60-90) (N = 1,547).
Participants rated the frequency of everyday memory failures using the 16-item Prospective and Retrospective Memory Questionnaire (PRMQ) and underwent objective memory testing at baseline. Participant self-reports of complaints of poor memory by family and friends were evaluated. Dementia status was followed-up for 10 to 12 years.
Over the study period, 225 participants developed dementia (132 with Alzheimer's disease (AD)). In Cox proportional hazard regression models adjusted for demographic factors, PRMQz-scores predicted incident dementia (hazard ratio (HR) = 1.21 for all-cause dementia; HR = 1.25 for AD, Ps