During our whole life span, factors influencing health and functioning are accumulated. In chronic kidney disease, quality of life is adversely affected. We hypothesized that biomarkers of renal function could also be determinants of subjective well-being (SWB) in Swedish elderly subjects. SWB was assessed by the Psychological General Well-Being index (PGWB index) in two study groups: Active seniors (AS) consisted of community-dwelling elderly Swedes leading an active life (n?=?389), and the DGM cohort (n?=?300) consisted of subjects referred to the Memory Unit at the Department of Geriatrics for memory problems, Serum creatinine, cystatin C, and eGFR (CKD-EPI) were used as biomarkers of renal function.
There were no significant differences in cystatin C and eGFR values between the two cohorts: cystatin C medians 0.88 vs 0.86 mg/L and eGFR 73 vs 80 mL/min/1.73 m2 (AS vs DGM). In the AS cohort cystatin C was negatively related to PGWB index in women (P?
Notes
Cites: Health Psychol. 2011 Nov;30(6):728-3521604881
Cites: Int Psychogeriatr. 2012 Feb;24(2):316-2322189624
Cites: N Engl J Med. 2012 Jul 5;367(1):20-922762315
Cites: Health Qual Life Outcomes. 2012;10:7122710013