A high mean-HbA1c value 3-15?months after diagnosis of type 1 diabetes in childhood is related to metabolic control, macroalbuminuria, and retinopathy in early adulthood--a pilot study using two nation-wide population based quality registries.
Intensive treatment of patients with type 1 diabetes delays the onset of long-term complications.
On the basis of the information from two nation-wide quality registers, we investigated to which extent HbA1c values 3-15?months after diagnosis in childhood are related to metabolic control, albuminuria, and retinopathy in early adulthood.
In Sweden, physicians register all children and adolescents with type 1 diabetes mellitus in the Swedish Pediatric Quality Registry. After 18?yr of age, people with diabetes are followed by the Swedish National Diabetes Register. We identified 1543 children and adolescents with a mean age of 13.9?yr at diagnosis and a mean duration of type 1 diabetes mellitus of 7.1?yr.
Children and adolescents with poor metabolic control (mean HbA1c = 70?mmol/mol (8.6 %)) adjacent to diagnosis had a significantly higher mean HbA1c value years later as adults than did patients with a good metabolic control [