To ascertain the relationship between cannabis use, obesity, and insulin resistance.
Data on 786 Inuit adults from the Nunavik Inuit Health Survey (2004) were analyzed. Information on cannabis use was obtained from a self-completed, confidential questionnaire. Fasting blood glucose and insulin and homeostasis model assessment of insulin resistance (HOMA-IR) served as surrogate markers of insulin resistance. Analysis of covariance and multivariate logistic regression ascertained relationships between cannabis use and outcomes.
Cannabis use was highly prevalent in the study population (57.4%) and was statistically associated with lower body mass index (BMI) (P