An account is given of the work done by scientists and practical workers in establishing and putting into operation an interregional research and practical complex of phthisio-pulmonology on the basis of three regional antituberculosis services of North-Western region of the Russian Federation (Novgorod, Pskov and Leningrad regions) and Leningrad Research Institute of Phthisio-pulmonology on the basis of economic mechanism of their interrelationships.