Alexithymic characteristics were assessed by the Toronto Alexithymia Scale (TAS), a self-report measure of alexithymia, in 230 consecutive outpatients referred to a psychiatric consultation-liaison service. The prevalence of alexithymia was 37.8% (50.5% in men and 28.2% in women). Alexithymia was significantly associated with the following variables: male gender, low socioeconomic status, the presence of psychiatric disorder, especially depression, with old age and with a high level of psychological distress. No significant association between alexithymia and the presence of somatic illness was found.