During the period of epidemic in the Daghestan 51 patients and 27 Vibrio carriers were detected in Makhachkala. A considerable proportion (30.7%) of cholera cases caused by infection imported from regions, unfavorable with respect to cholera, in the presence of pronounced migration of the population was registered. The role of different transmission routes in cases of cholera was as follows: day contacts were responsible for 43.3%, the alimentary route for 28.4% and the water route for 14.9% of cases. The epidemic situation was characterized by a mild and prolonged type of the epidemic process. Mass diseases were prevented by a complex of cholera control measures, among them the emphasis was made on various limitations and prophylactic measures aimed at the rupture of the transmission routes of V. cholerae.