The implication of meteorological factors in the incidence of acute urinary retention (AUR) were studied in prostatic adenoma patients. The trial was performed in the city of Perm (population 1.1 million) situated in the temperate zone with continental climate. The only center for emergency urological aid registered all AUR cases observed in the city throughout 1980-1990. All 1504 episodes of AUR were recorded with reference to meteorological conditions on the day of admission (temperature, atmospheric pressure, etc.). The original data obtained after mathematical processing of the material indicate that AUR frequency goes up in day-to-day temperature fluctuations (5 degrees C and more), changes in atmospheric pressure (9 GPa and more) and in humidity (20% or more); in moderate and strong winds, cloudy wet weather, thunder storms. A complex of general and pharmacological measures is proposed to prevent AUR episodes in patients with prostatic adenoma.