Results were analyzed of diagnosis and treatment of 314 patients with malignant tumours of the liver. Of these, 36 had primary tumours of the liver (PTL), 278 were presenting with metastatic tumours (MTL). In addition, an analysis was carried out in 1236 oncological patients in order that the frequency of metastasizing of tumours into the liver might be determined together with the specific weight of metastases of different locations. The rates of tumours metastasizing to the liver were found out to be 45.7, 33.3, 30.1 percent with the gallbladder, major duodenal papilla, stomach respectively. Ultrasonography is an effective diagnostic tool for malignant tumours of the liver, being of great informative value (sensitivity in PTL--97.2%, MTL--75.7%). Eight (22.2%) patients with PTL and seventeen (6.1%) ones with MTL underwent surgical treatment. The only radical modality of treatment is still anatomical resection of the liver. Investigations are under way designed to study efficiency of thermo-(cryo) destruction of solitary and single liver metastases if surgical resection is beyond the bounds of possibility.