Leading principles of DOTS strategy for Russia are outlined. It has been introduced in Russia since 1994 in Ivanovo, Tomsk Regions, Mary El Republic. New territories (Leningrad and Arkhangelsk Regions) have recently joined the project. Methods of detecting bacillary patients, scheme of chemotherapy for different tuberculosis patients and of bacteriological and x-ray follow-up control are presented. Positive aspects of the program are analyzed as well as causes of its insufficient benefit under conditions of Russian Federation.