Incidence of first stroke and stroke mortality in Krasnodar in 1997-2000 were higher compared with data of similar registers in Moskva and Novosibirsk. Hospitalization rate of patients with stroke especially of those with severe stroke was low with high 28 days and 1 year mortality. Main risk factor of stroke was hypertension which in about 2 thirds of patients was classified as mild. Half of the patients with hypertension had history of hypertensive crises. Despite high level of awareness about presence of hypertension only every tenth patient received regular antihypertensive therapy which however in most cases was ineffective. One half of the patients received no antihypertensive treatment at all. Even after stroke most of the patients did not take antihypertensive drugs and antiaggregants. Results of the register show that there exists a great deal of resource for implementation of standard measures aimed at primary and secondary stroke prevention and lowering of mortality of patients with stroke.