The specific features of the clinical presentation and course of respiratory sarcoidosis (S) and the efficiency of its treatment were studied in 109 new cases in the Perm Region. The incidence of S is higher among residents from towns with developed heavy industry, mainly in females. Primary chronic S was predominant (89.9%). The efficiency of treatment in the patients was 69.5%. The results of treatment were worse in the untimely detection of S. The recovery rates were higher with corticosteroid tablets used continuously (87.5%) and those were lower with their intermittent use (82.9%).