The disability of the population of the able-bodied age causes an essential social-and-economic damage to society, because the whole "labor resource" and "the resource" ensuring the reproduction of new generations are concentrated within the mentioned life age interval. A 9-year profound study of the primary disability among the citizens of the Perm Region led to defining the main regularities and trends of prevalence and of causes of getting disabled. A forecast of the process of the able-bodied population getting disabled was made until 2005 for the whole region and for the main categories of diseases; solutions to resolving the discussed problem are defined.