Analyzed data demonstrates that both in rural areas and all over the Russian Federation in spite of that certain decreasing of particular invalidity indicators begins to show, still it is not possible to consider these indicators as stabilized. The reason being in impact on invalidity formation of overall complex of climatic geographic, demographic, social, medical and economic factors. Lower effectiveness of rehabilitation activities, including reluctance of invalids themselves, contributes to retention of higher incidence of general invalidity. Lacking of adequate and statistically reliable registration of invalidity of adolescent population breaks system of medical demographic indicators. In view of the aforesaid it is needed to carry out systematic analysis of cause-and-effect relations to ensure differentiated approach in managing activities and administrative decision-making to reduce invalidity rate.