A retrospective study of 594 medical histories of patients with surgical infections suggested diagnosis of sepsis in 18.2% cases according to ACCP/SCCM criteria (1992). Pulmonary and abdominal sepsis prevailed and led to higher lethality. Sepsis developed most often as nosocomial infection caused primarily by Acinetobacter spp. and Ps.aeruginosa. Most patients were males aged from 40 to 60 years. The main causes of lethality were septic shock (49.3%) and multiple organ failure syndrome (21%). Time of surgical sanation, antibacterial therapy and its adequacy correlated with the disease outcome.