The representative group of women older than 40 years with oncological gynecological pathology during involution period was examined. Quality of life of these patients and their attitude to their health as well was studied during various rehabilitation periods of the course of this disease. Survey was applied using questionnaire MOS-SF 36 Health Survey 2.0 with subsequent statistical data processing. The results can be applied to enhance effectiveness of preventive activities in gynecology and practical and research medicine.